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Knowledge of the factors that predispose certain individuals to experience adverse effects could open the way to increasing the safety profile of vaccines

It has been described as an L-threonine metabolite which correlates negatively with age in adults 61 , but has to our knowledge not been linked directly to PD

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Macrophages can also display antigen-presenting activity by expressing major histocompatibility class (MHC), leading to a cross-talk between innate and cell-mediated immune system